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5. Chelation of GRP78 with Lead and Its Localization Changes in the Astroglia of Rats Exposed to Lead

Chelation of GRP78 with Lead and Its Localization Changes in the Astroglia of Rats Exposed to Lead

来源 :华中科技大学学报（医学）（英德文版） | 被引量 : 0次 | 上传用户：janson2403

【摘 要】

：

remarkably increase when it transferred from ER to the cytosol around the nuclei 24 h after treatment with Pb. It is concluded that GRP78 in astroglia could str

【作 者】

：

Ying ZHANG Liping YE Biao WANG 

【机 构】

：

Institute of Neurology,Department of Pathophysiology,Department of Biochemistry and Molecule Biology

【出 处】

：

华中科技大学学报（医学）（英德文版）

【发表日期】

：

2004年期

【关键词】

：

lead astroglia GRP78 chelation 

【基金项目】

：

国家自然科学基金

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remarkably increase when it transferred from ER to the cytosol around the nuclei 24 h after treatment with Pb. It is concluded that GRP78 in astroglia could strongly chelate with Pb ions and it might be a target protein of Pb.

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