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胺先质摄取及脱羧作用(APUD)系统与人体不同部位的某些细胞和肿瘤有密切联系,据文献报道可发生于肺、胃及其他部位。本文首次报道一例肝细胞肝癌伴类癌的肝肿瘤。患者43岁,男性,主诉右上腺肿胀。剖腹探查发现肝内有一大肿块,HBsAg阳性,AFP增高,主要波及右叶,邻近肝叶有硬化,但无肿瘤浸润。附近大网膜见数个肿瘤结节。因肿瘤不能切除改为化疗,病人因肝功能衰竭而死亡。从诊断到死亡共26个月, 病理检查活检组织取自肝内肿块及大网膜结节。镜检肿瘤结节有典型的肝细胞肝癌特征,即核大、
The amine precursor uptake and decarboxylation (APUD) system is closely related to certain cells and tumors in different parts of the human body and has been reported in the literature to occur in the lungs, stomach, and other areas. This article first reported a case of hepatocellular carcinoma with carcinoid liver tumors. The patient, 43 years old, was male and complained of swelling of the right upper lobe. The exploratory laparotomy revealed a large mass in the liver, with positive HBsAg, increased AFP, mainly affecting the right lobe, and adjacent jugular sclerosis, but no tumor infiltration. See a few omental nodules in the omentum nearby. The patient died of hepatic failure because the tumor could not be removed and chemotherapy was replaced. From the diagnosis to death for a total of 26 months, pathological biopsies were taken from intrahepatic masses and omental nodules. Microscopic examination of tumor nodules has typical characteristics of hepatocellular carcinoma.