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目的:探讨混苯对女工月经的影响及血清七种元素的变化。方法:采用调查表的方法统一调查女工月经的变化;用电感耦合等离子体放射光谱法测定血清七种元素含量。结果:(1) 直接接触组及间接接触组女工月经异常的发生率均明显高于对照组(P< 0 .005) ,主要为月经周期缩短和经量增多,直接接触组月经异常发生率明显高于间接接触组(P< 0 .005) ;(2) 接触组血清Ca、P、Cu 、Mn 、Zn 、Fe 及Zn/Cu 比值均明显低于对照组(P均< 0 .05) ,而血清Mg 含量及Fe/Cu 比值两组间无显著差异(P> 0 .05) 。结论:(1) 混苯可能是通过大脑皮层引起内分泌紊乱,导致月经异常;接触混苯的机会与内分泌紊乱呈正相关趋势;(2) 混苯可能通过影响血清元素的吸收、分布或代谢的某一过程,致使接触组血清六种元素明显减少。
Objective: To investigate the effects of mixed benzene on menstrual cramps and the changes of seven elements in serum. Methods: A questionnaire survey was conducted to investigate the changes of women’s menstruation. The contents of seven elements in serum were determined by inductively coupled plasma atomic emission spectrometry. Results: (1) The incidences of menstrual abnormalities in direct contact group and indirect contact group were significantly higher than those in control group (P <0 .005), mainly due to shortening menstrual cycle and increasing the amount of menstruation, and the incidence of abnormal menstruation in direct contact group was significantly (2) The serum Ca, P, Cu, Mn, Zn, Fe and Zn / Cu ratios in the exposed group were significantly lower than those in the control group (all P <0. 05) The serum Mg content and Fe / Cu ratio had no significant difference between the two groups (P> 0.05). Conclusion: (1) Mixed benzene may cause endocrine disorder through the cerebral cortex, leading to abnormal menstruation; the chance of exposure to mixed benzene is positively correlated with endocrine disorders; (2) Mixed benzene may affect the absorption, distribution or metabolism of serum elements A process, resulting in contact group serum six elements significantly reduced.