安痛定注射液含氨基比林5%、安替比林2%、巴比妥0.8965%或巴比妥钠1%。氨基比林易氧化生成双氧氨基比林而呈色,安替比林也会氧化,但比氨基比林安定些。氨基比林与巴比妥配伍更易变色,由于它在酸性或中性溶液中更易氧化。本剂原料如为巴比妥时,制品pH约为6.5左右,不安定,需要调整到8.2～8.4。如采用巴比妥钠为原料时,其pH在9左右,较安定。 Antongding injection contains 5% aminopyrine, 2% antipyrine, 0.8965% barbiturate or 1% sodium pentobarbital. Aminopyrine easily oxidized to generate diamino aminopyrine and color, antipyrine oxidation, but more stable than aminopyrine. Aminopyrine and barbiturates are more susceptible to discoloration due to their tendency to oxidize in acidic or neutral solutions. The raw materials such as barbiturates when the product pH is about 6.5, restless, need to be adjusted to 8.2 ~ 8.4. Such as the use of sodium pentobarbital as the raw material, the pH at about 9, more stable.