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本刊从这期开始陆续刊登上海医药工业研究院与各兄弟厂一起研制的薄膜新剂型,包括口服安定药膜、苯乙哌啶药膜、外用避孕药膜、眼用毛果芸香碱药膜、舌下硝酸甘油含膜以及药膜制膜机、药膜包装机等方面的文章。薄膜剂型是适合于小剂量药物的一种新颖制剂,可制成口服、阴道用、皮肤创伤用、植入用、眼用、舌下含服等剂型。它工艺简单,易解决劳动保护问题,易实现连动化生产;可制成多层复合膜以制备复方,解决复方的分析干扰、配伍禁忌;选用不同的成膜材科,尚可制备速效、长效药膜等等,因而是一种很有希望的新剂型。由于研制的时间不长,目前还存在一些问题,请广大读者能提供宝贵意见。
From the beginning of this issue one after another published in Shanghai Institute of Pharmaceutical Industry with the brothers plant together developed a new type of film formulations, including oral stability of the film, diphenoxylate film, topical contraceptive film, ophthalmic pilocarpine film, sublingual Nitroglycerin-containing film and film coating machine, film packaging machine and other aspects of the article. Film dosage forms are a novel formulation suitable for small doses of drugs, which can be formulated for oral, vaginal, dermal wound, implants, ophthalmic and sublingual dosage forms. The utility model has the advantages of simple process, easy solution to the problem of labor protection and easy realization of interlocking production; can be made into a multi-layer composite membrane to prepare the compound to solve the analysis interference and incompatibility of the compound; selecting different film forming materials, Long-acting membrane and so on, so it is a promising new dosage form. Due to the development of a short time, there are still some problems, please readers can provide valuable advice.