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四环素族抗菌素包括:金霉素(氯四环素)、土霉素(氧四环素)、四环案及一些新的衍生物。他們都具有同样的母核——四个駢联的六元环,故得名;同时他們的抗菌性质、药理作用及临床应用均有相似之处。四环素族的抗菌譜广、治疗范围广、毒性較低、可以口服,因此該族已广泛用于临床,頗得好評。性状金霉素、土霉素、四环素均为黄色結晶性粉末,无臭,味苦,在PH7时微溶于水(0.25—
Tetracycline antibiotics include: chlortetracycline (chlortetracycline), oxytetracycline (oxytetracycline), tetracyclic and some new derivatives. They all have the same mother nucleus - four couplet six-membered ring, hence the name; at the same time their antimicrobial properties, pharmacological effects and clinical applications are similarities. Tetracycline wide antibacterial spectrum, the treatment of a wide range of low toxicity, can be oral, so the family has been widely used in clinical, rather well received. Characters chlortetracycline, oxytetracycline, tetracycline are yellow crystalline powder, odorless, bitter, slightly soluble in water at pH 7 (0.25-