目的探讨2005―2015年来宾市伤寒副伤寒流行特征及传播因素,为制定新时期防控策略提供科学依据。方法对来宾市2005―2015年伤寒副伤寒疫情资料进行描述流行病学分析。结果 2005―2015年来宾市共报告伤寒副伤寒383例,年均发病率为1.58/10万。全市6个县(市、区)均有病例发生,年均发病率最高为合山市5.83/10万,其次为象州县3.04/10万。全年各月均有病例发生,其中以10月病例数最多(70例),占病例总数的18.28%,其次为4、6月,均为51例,分别占13.32%。各年龄组均有发病,其中以10~19和≥65岁年龄组病例数最多,合计占43.34%;男性194例,女性189例,男女性别比为1.03∶1。病例以农民、学生为主,分别占47.78%(183例)、28.98%(111例)。结论来宾市属于伤寒副伤寒低发地区,以散发为主,农民和学生是需要重点干预的人群。 Objective To explore the epidemiological characteristics and transmission factors of typhoid and paratyphoid fever in Laibin city from 2005 to 2015, and to provide a scientific basis for formulating prevention and control strategies in the new era. Methods Epidemiological analysis of epidemic data of typhoid and paratyphoid fever in Laibin from 2005 to 2015 was performed. Results A total of 383 cases of typhoid and paratyphoid fever were reported in Laibin City from 2005 to 2015, with an average annual incidence of 1.58 / 100,000. The city’s six counties (cities, districts) have cases, the highest annual average incidence of 5.83 / 100,000 in Heshan City, followed by Xiangzhou 3.04 / 100,000. Cases occurred in all months of the year, of which the highest number of cases in October (70 cases), accounting for 18.28% of the total number of cases, followed by April and June, were 51 cases, accounting for 13.32%. The incidence of all age groups, of which 10 to 19 and ≥ 65 years of age group, the largest number, accounting for 43.34%; 194 were male and 189 women, male to female ratio was 1.03: 1. The cases were mainly farmers and students, accounting for 47.78% (183 cases) and 28.98% (111 cases) respectively. Conclusions Laibin belongs to the low incidence area of ​​typhoid and paratyphoid fever, with the main distribution, while the peasants and students are the people who need the key intervention.