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目的观察奥曲肽治疗对消化道出血患者不良反应的影响,分析其临床效果和安全性。方法选取医院收治的消化道出血患者100例,随机分为对照组和观察组,每组50例。对照组给予常规药物治疗,观察组采用奥曲肽治疗,观察2组临床治疗效果及不良反应发生情况。结果观察组治疗总有效率为92.0%,显著高于对照组的76.0%(P<0.01);观察组再出血率显著低于对照组,止血时间明显短于对照组,差异均有统计学意义(P<0.01)。观察组不良反应发生率为8.0%,低于对照组的20.0%(P<0.05)。结论奥曲肽治疗能够显著降低消化道出血患者的不良反应发生率,患者出现再出血率低,止血时间短,临床效果显著。
Objective To observe the effect of octreotide treatment on adverse reactions in patients with gastrointestinal bleeding and analyze its clinical effect and safety. Methods 100 cases of patients with gastrointestinal bleeding admitted to the hospital were randomly divided into control group and observation group, 50 cases in each group. The control group was given conventional drug treatment, the observation group was treated with octreotide, and the clinical effects and adverse reactions of the two groups were observed. Results The total effective rate of observation group was 92.0%, which was significantly higher than that of control group (76.0%, P <0.01). The rebleeding rate of observation group was significantly lower than that of control group, and the bleeding time was significantly shorter than that of control group (P <0.01). The incidence of adverse reactions in the observation group was 8.0%, which was lower than that in the control group (20.0%, P <0.05). Conclusion The octreotide treatment can significantly reduce the incidence of adverse reactions in patients with gastrointestinal bleeding, patients with low recurrence rate, bleeding time is short, the clinical effect was significant.