对某镍矿进行了恶性肿瘤回顾性队列研究,应调查男职工1959人,失访1人,观察17年,共获得32515.5人年。结果表明,该队列全死因,恶性肿瘤粗死亡率高于一般人群,但差异无显著性。肺癌粗死亡率是24.60/10万(冶炼组是30.09/10万),以全国、会理县男性肺癌死亡专率作参比标准,标化死亡比(SMR)达229.89、975.61,具有统计学意义。肺癌病例从首次接镍作业到肺癌死亡,平均间隔22.3年,肺癌平均死亡年龄54.8岁。本研究结果表明,该矿接触硫化物镍的镍熔炼工肺癌危险度增高。 A retrospective cohort study on malignant tumors of a nickel mine should investigate 1,959 men and 1 missing person and observe 17 years and obtain a total of 32515.5 person years. The results showed that the cohort of all causes of death, malignant tumor crude mortality was higher than the general population, but the difference was not significant. The crude death rate of lung cancer was 24.60 / 100000 (the smelting group was 30.09 / 100000). The standard of death rate (SMR) was 229.89 and 975.61 for male patients with lung cancer in Huili County, China. Statistical significance significance. Lung cancer cases from the first nickel operation to lung cancer deaths, with an average interval of 22.3 years, the average age of lung cancer death was 54.8 years old. The results of this study show that the mine is exposed to sulfide nickel nickel smelting workers increased the risk of lung cancer.