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IL-2研究的一般状况白细胞介素-2(Interleukin-2,IL-2)是一种主要由T_H细胞产生的淋巴因子,Morgan(1976)发现在体外培养对肿瘤有特异杀伤作用的T细胞过程中,需加入一种由人骨髓细胞提取的生长因子,因此,也称其为T细胞生长因子(TCGF),而后随着对其生物学活性及生化特性的不断研究,发现IL-2有种属特异性,Smith(1983)研究出可识别人类IL-2的单克隆抗体,Taniguchi等(1983)利用分子克隆技术确定了人的IL-2
General Status of IL-2 Studies Interleukin-2 (IL-2), a lymphokine predominantly produced by T-H cells, was found by Morgan (1976) in vitro to develop T cells that are specifically damaging to tumors In the process, it is necessary to add a growth factor extracted from human bone marrow cells, therefore, also known as T-cell growth factor (TCGF), and then with its biological activity and biochemical characteristics of continuous research and found IL-2 Species-specific, Smith (1983) developed a monoclonal antibody that recognizes human IL-2. Taniguchi et al. (1983) used molecular cloning to determine the human IL-2