论文部分内容阅读
目的比较托拉塞米与呋塞米治疗充血性心力衰竭的临床疗效。方法选取2012年4月—2015年3月德阳市人民医院收治的充血性心力衰竭患者152例,按随机数字表法分为研究组与对照组,各76例。研究组患者予以托拉塞米治疗,对照组患者予以呋塞米治疗。观察两组患者临床疗效、体质量、血钾水平、24h尿量增量及不良反应(头晕、乏力、心律失常、低钾血症)发生情况。结果研究组患者总有效率高于对照组,差异有统计学意义(P<0.05);研究组患者体质量低于对照组,血钾水平、24h尿量增量高于对照组,差异有统计学意义(P<0.05);研究组患者不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论托拉塞米治疗充血性心力衰竭的临床疗效优于呋塞米,托拉塞米能改善患者临床疗效,且不良反应少。
Objective To compare the clinical efficacy of torsemide and furosemide in the treatment of congestive heart failure. Methods 152 patients with congestive heart failure admitted to Deyang People’s Hospital from April 2012 to March 2015 were randomly divided into study group and control group with 76 cases in each group. Patients in the study group were treated with torsemide, and patients in the control group were treated with furosemide. The clinical curative effect, body weight, serum potassium level, urine volume increase in 24 hours and the occurrence of adverse reactions (dizziness, fatigue, arrhythmia, hypokalemia) were observed. Results The total effective rate of the study group was higher than that of the control group (P <0.05). The body weight of the study group was lower than that of the control group. The serum potassium level and 24h urine volume increase were higher than those of the control group (P <0.05). The incidence of adverse reactions in study group was lower than that in control group (P <0.05). Conclusion Torasemide is superior to furosemide in the treatment of congestive heart failure. Torsemide improves the clinical efficacy and has fewer adverse reactions.