本病在1936年由Freudenthal首先命名为角化棘皮瘤.早在19世纪末叶Hutchinson曾描述过一种和本病相类似的“面部火山口状溃疡”的病变.同义的名称尚有:皮脂性软疣、假癌性软疣、类肿瘤角化病、特发性皮肤假上皮瘤性增生、可自然痊愈的皮肤多发性原发鳞状细胞癌以及自愈的原发性鳞癌.本病在临床上主要有两种类型:即多发性和局限性或孤立性.以局限性或孤立性更为常见.病变 The disease was first named as keratoacanthoma by Freudenthal in 1936. As early as the end of the 19th century, Hutchinson described a “face crater ulcer” similar to the disease. Synonymous names are still available. : sebaceous soft palate, pseudocarcinoma soft palate, paraneoplastic keratosis, idiopathic pseudoepitheliomatous hyperplasia, spontaneously recoverable multiple primary squamous cell carcinoma of the skin and self-healing primary squamous cell carcinoma There are two major types of this disease in clinical practice: multiple and localized or solitary, with limitations or isolation more common.