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幽门螺杆菌感染在急性冠脉综合征发病机理和进展中的作用越来越被重视,但具体机制仍是不清楚的。现在被证实在血清流行病学方面和根除术研究中与急性冠脉综合征有着因果联系,但这个话题仍然受到争议。从冠脉粥样斑块物质中检测到的幽门螺杆菌特异性DNA及其细胞毒素相关基因A抗体阳性与临床症状之间的联系可以解释急性冠脉综合征的发生发展是由一个局部炎性过程引起的。
The role of Helicobacter pylori infection in the pathogenesis and progression of acute coronary syndrome is gaining more and more attention, but the exact mechanism remains unclear. It is now confirmed that there is a causal link between acute coronary syndromes in serological epidemiology and eradication studies, but the topic remains controversial. The association of H. pylori-specific DNA and its cytotoxic-related gene A antibody positive with clinical symptoms detected from coronary atherosclerotic plaque material may explain the development of acute coronary syndromes as a result of a local inflammatory Process caused.