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应用韦氏成人智力量表（ＷＡＩＳ－ＲＣ）及事件相关电位（ＥＲＰ，Ｐ３００）对癫痫患者的智能损害进行评价，发现总智商（ＦＩＱ）低于正常者占４８．４８％，而Ｐ３００异常率为５１．６％。影响因素分析表明：发作频度越高，抗癫痫药物（ＡＥＤｓ）越多，病程越长，初发年龄越小，脑电图（ＥＥＧ）改变越重，其智能的损害越严重。其中发作频度对智能障碍影响最大，ＡＥＤｓ次之。Ｐ３００与癫痫各级的智能（ＦＩＱ）关系表明，Ｐ３００有可能成为反映癫痫患者智能障碍动态变化的客观指标之一。
WAIS-RC and ERP (P300) were used to evaluate the intelligence impairment in patients with epilepsy and found that the rate of FIQ was 48.48% lower than normal, while the rate of P300 abnormality For 51.6%. The analysis of influencing factors showed that the higher the frequency of seizures, the more antiepileptic drugs (AEDs), the longer the course of disease, the younger the age of onset, the more severe the change of EEG and the more severe the damage of intelligence. Among them, the frequency of seizures had the greatest impact on mental retardation, followed by AEDs. P300 and epilepsy at all levels of intelligence (FIQ) relationship shows that P300 may become one of the objective indicators reflecting the dynamic changes in patients with intellectual disorders of epilepsy.