益生菌活菌制剂联合肠内营养治疗重症脑卒中患者的临床效果

来源 :中国药物经济学 | 被引量 : 0次 | 上传用户:sqe622
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目的探讨益生菌活菌制剂联合肠内营养治疗重症脑卒中患者的临床效果。方法选取2012年3月至2016年3月辽宁省本溪市中心医院收治的120例重症脑卒中患者作为研究对象,按随机数字表法将其分为试验组与对照组,各60例。对照组患者实施肠内营养支持治疗,试验组患者在对照组基础上采用益生菌活菌制剂进行治疗,比较两组患者治疗效果。结果试验组患者的不良反应发生率明显低于对照组,差异有统计学意义(P<0.05);试验组患者消化道出血、肺部感染及泌尿系统感染发生率均明显低于对照组,差异均有统计学意义(均P<0.05);试验组患者营养液达供给量时间明显短于对照组,菌群失调率明显低于对照组,差异均有统计学意义(均P<0.05)。结论针对重症脑卒中患者,在肠内营养支持治疗基础上,联合益生菌活菌制剂进行治疗,效果显著且安全可靠。 Objective To investigate the clinical effect of live probiotics combined with enteral nutrition in the treatment of severe stroke patients. Methods A total of 120 severe stroke patients admitted to the Central Hospital of Benxi City in Liaoning Province from March 2012 to March 2016 were selected as study subjects and divided into experimental group and control group according to random number table method, with 60 cases in each group. Patients in the control group were enrolled in enteral nutrition support. Patients in the test group were treated with probiotic viable bacteria on the basis of the control group, and the treatment effect was compared between the two groups. Results The incidence of adverse reactions in the experimental group was significantly lower than that in the control group (P <0.05). The incidences of gastrointestinal bleeding, lung infection and urinary tract infection in the experimental group were significantly lower than those in the control group (All P <0.05). The supply time of nutrient solution in the experimental group was significantly shorter than that in the control group, and the imbalance rate of the bacteria group was significantly lower than that of the control group (all P <0.05). Conclusions For patients with severe stroke, based on the enteral nutrition supportive therapy, probiotics combined with probiotics for treatment, the effect is significant and safe and reliable.
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