2009年7月～2010年11月,我们对45例恶性胸腔积液患者实施胸腔内灌注甘露聚糖肽联合顺铂治疗,取得满意效果。现报告如下。1资料与方法1.1临床资料本组恶性胸腔积液患者84例,男51例,女33例;平均56岁。所有患者自1个月内均未接受化疗或放疗,功能状态评分标准(KPS)评分>60分,均无化疗禁忌证, July 2009 to November 2010, we performed 45 cases of malignant pleural effusion in patients with intrapleural perfusion of mannan plus cisplatin, and achieved satisfactory results. The report is as follows. 1 Materials and Methods 1.1 Clinical data 84 patients with malignant pleural effusion in this group, 51 males and 33 females; mean 56 years. All patients did not receive chemotherapy or radiotherapy within 1 month, and KPS score> 60, no chemotherapy contraindications,