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高热是儿科疾病中最常见的病状,目前在治疗中退热效果较好的均为口服或注射用药,使患儿难以接受。为此,我们于1992年3月研制了“熊胆退热栓”肛门栓。经我院儿科对110例外因和内伤引起的高热观察表明,此药具有退热快、作用时间长、无毒副作用等特点,有效率为95.5%。一、处方熊胆细粉(过80目筛)5g,PVA-400028g,PVA-6000 37g,甘油7g,蒸馏水24ml,共制100粒。二、制备方法将基质置水浴上加热熔融,加入熊胆细粉搅匀,趁热倾入涂有润滑剂(液体石蜡)的栓模内,使稍溢出模口,待冷却成型后,削去多余部分,取出包装备用。三、质量控制
Hyperthermia is the most common condition in pediatric diseases. At present, the most effective antipyretics in treatment are oral or injectable drugs, making it difficult for children to accept. To this end, we developed the “bear bile fever antithrombotic” anus thrombus in March 1992. The observation of high fever caused by the 110-cause and internal injuries in our hospital’s pediatric department showed that the drug had the characteristics of rapid fever reduction, long duration of action, no toxic and side effects, and the effective rate was 95.5%. First, the prescription bear bile powder (over 80 mesh sieve) 5g, PVA-400028g, PVA-6000 37g, glycerin 7g, distilled water 24ml, a total of 100 tablets. Second, the preparation method The matrix is placed on a water bath heated to melt, add bear bile powder mix, while hot poured into a lubricant coated with (liquid paraffin) plug, so that a little overflow die, to be cooled after molding, pare Excess parts, remove the package for use. Third, quality control