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目的:观察在西药治疗基础上以健脾化湿汤内服和灌肠方保留灌肠治疗慢性结肠炎脾胃虚弱证患者的疗效。方法:筛选本院收治的90例慢性结肠炎脾胃虚弱证病例,随机分为观察组和对照各45例。对照组口服柳氮磺吡啶肠溶片,观察组在对照组治疗基础上给予健脾化湿汤内服和灌肠方保留灌肠治疗。2组疗程均为8周。比较2组的临床疗效、中医症状评分、Southerland疾病活动指数评分。结果:观察组总有效率为95.56%,高于对照组的75.56%,差异有统计学意义(P<0.05)。治疗后,观察组各项中医症状评分均较治疗前降低(P<0.01),且低于对照组,差异均有统计学意义(P<0.01);2组腹泻、脓血便、黏膜表现及医师病情评估评分均较治疗前降低(P<0.01);观察组各项评分均低于对照组,差异均有统计学意义(P<0.01)。结论:在西药治疗基础上予健脾化湿汤内服和灌肠方保留灌肠治疗慢性结肠炎脾胃虚弱证,可明显改善患者的中医临床症状和Southerland疾病活动指数,提高临床疗效。
OBJECTIVE: To observe the curative effect of treating patients with spleen-stomach deficiency syndrome of chronic colitis with Jianpi Huashi Decoction and enema enema on the basis of Western medicine treatment. Methods: 90 cases of chronic deficiency of spleen and stomach in patients with chronic colitis were screened and randomly divided into observation group and control group with 45 cases each. The control group was orally administered with sulfasalazine enteric-coated tablets. The observation group was given Jianpi Huashi Decoction orally and enema-preserving enema on the basis of the control group. The two groups were treated for 8 weeks. The clinical efficacy, TCM symptom score and Southerland disease activity index were compared between the two groups. Results: The total effective rate in the observation group was 95.56%, which was higher than that in the control group (75.56%), the difference was statistically significant (P <0.05). After treatment, the scores of TCM symptoms in the observation group were lower than those before treatment (P <0.01), and were lower than those in the control group (P <0.01). Diarrhea, pus and blood stool, The score of disease evaluation was lower than that before treatment (P <0.01). The score of the observation group was lower than that of the control group, the difference was statistically significant (P <0.01). Conclusion: Based on the western medicine, Jianpi Huashi Decoction and enema enema for the treatment of chronic deficiency of spleen and stomach of chronic colitis can significantly improve the clinical symptoms and Southerland disease activity index of patients and improve the clinical curative effect.