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目的 :探索药物治疗不稳定性心绞痛尽可能合理的方案。方法 :将 6 5例不稳定性心绞痛患者随机分为A、B、C三组 ,在常规治疗的基础上分别将各组心室率控制在 5 0～ 6 0次 /min、6 1～ 79次 /min和≥ 80次 /min ,血压控制在≤ 110 / 70mmHg、111～ 139/ 71～ 89mmHg和≥ 14 0 / 90mmHg ,观察各组临床症状改善程度及运动耐量、生活质量的变化。结果 :心室率和血压水平控制得越低 ,患者心绞痛发作次数及硝酸甘油用量越少 ,运动耐量增加越明显 ,生活质量也越好。结论 :不稳定性心绞痛患者在常规治疗的基础上 ,将心室率和血压控制在尽量低的水平 ,有助于最大程度地改善患者的临床症状、运动耐量和生活质量。
OBJECTIVE: To explore the most plausible protocol for drug treatment of unstable angina pectoris. Methods: Sixty-five patients with unstable angina were randomly divided into three groups: A, B and C. On the basis of routine treatment, the ventricular rate of each group was controlled at 50 ~ 60 times / min and 61 ~ 79 times Blood pressure was controlled at ≤110 / 70mmHg, 111 ~ 139/71 ~ 89mmHg and ≥14 0 / 90mmHg. The changes of clinical symptoms, exercise tolerance and quality of life in each group were observed. Results: The lower the control of ventricular rate and blood pressure, the lower the number of patients with angina attacks and the amount of nitroglycerin, exercise tolerance increased significantly, the better the quality of life. CONCLUSIONS: Patients with unstable angina pectoris have ventricular rate and blood pressure controlled as low as possible on a routine basis, helping to maximize clinical symptoms, exercise tolerance, and quality of life.