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目的探讨低管电压联合低剂量、低流速对比剂扫描方法在冠状动脉CT血管成像(CCTA)中的应用及其可行性。方法对2014年5月至11月80例冠心病患者行CCTA。随机分成两组:A组采用70 ml对比剂剂量,注射速率5.0 ml/s,管电压120 k V,滤波反投影(BFP)重建成像;B组采用50 ml对比剂剂量,注射速率4.0 ml/s,管电压100 k V,迭代重建算法重建成像。分别采用主观评价法和客观评价法对两组图像质量以及冠状动脉强化的平均值(SI4)、图像信号噪声比(SNR)、对比度噪声比(CNR)、背景噪声(BN)和辐射有效剂量(ED)进行评估。结果 A组图像质量评分为(3.75±0.25)分,B组为(3.73±0.24)分,两组比较差异无统计学意义(t=0.047,P>0.05)。A组SI4值(428.15±50.95)Hu,B组SI4值(435.90±58.90)Hu,两组比较差异无统计学意义(t=0.339,P>0.05);A组BN值(30.39±6.35)Hu,B组BN值(29.47±5.18)Hu,两组比较差异无统计学意义(t=0.686,P>0.05);A组SNR值(14.32±1.82)Hu,B组SNR值(14.04±2.22)Hu,两组比较差异无统计学意义(t=0.324,P>0.05);A组CNR值(11.78±1.49)Hu,B组CNR值(11.70±1.89)Hu,两组比较差异无统计学意义(t=0.108,P>0.05)。A组ED值为(8.09±0.41)m Sv,B组ED值为(4.77±0.29)m Sv,B组ED值明显低于A组(t=22.295,P<0.01)。结论低管电压联合低剂量、低流速对比剂扫描方法在保证图像质量的同时,减少了对比剂剂量,降低了辐射剂量,对于冠心病的筛查、术前评估、术后随访是可行的。
Objective To investigate the feasibility and feasibility of low-voltage combined with low-dose and low-flow contrast agent scanning in coronary CT angiography (CCTA). Methods From May 2014 to November 2014, 80 patients with coronary heart disease underwent CCTA. The rats were randomly divided into two groups: group A received a dose of 70 ml, a rate of 5.0 ml / s, a voltage of 120 kV and a BFP reconstruction. Group B received a dose of 50 ml with an injection rate of 4.0 ml / s, tube voltage 100 kV, iterative reconstruction algorithm reconstruction imaging. Subjective evaluation and objective evaluation were used to evaluate the differences of image quality, mean of SI4, SNR, CNR, BN and radiation effective dose (ED) for evaluation. Results The image quality score was (3.75 ± 0.25) in group A and (3.73 ± 0.24) in group B, respectively. There was no significant difference between the two groups (t = 0.047, P> 0.05). The SI4 value in group A (428.15 ± 50.95) Hu and the value of SI4 in group B (435.90 ± 58.90) Hu were not significantly different between the two groups (t = 0.339, P> 0.05) (14.42 +/- 1.82) Hu and B (14.04 +/- 2.22) in group B, and BN in group B (29.47 +/- 5.18) Hu was no significant difference between the two groups (t = 0.686, Hu, there was no significant difference between the two groups (t = 0.324, P> 0.05); CNR of group A was (11.78 ± 1.49) Hu and that of group B was (11.70 ± 1.89) Hu. There was no significant difference between the two groups (t = 0.108, P> 0.05). The ED of group A was (8.09 ± 0.41) m Sv, that of group B was (4.77 ± 0.29) m Sv, and that of group B was significantly lower than that of group A (t = 22.295, P <0.01). Conclusions The low-voltage and low-flow contrast agent scanning method can reduce the dose of contrast medium and reduce the radiation dose while ensuring the image quality. It is feasible to screen coronary artery disease, evaluate it before operation and follow-up after operation.