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目的探求女性乳腺癌的危险因素,为乳腺癌的防治提供依据。方法采用病例对照研究方法,问卷调查2003年1月~2005年4月入院的经病理组织学确诊的女性乳腺癌生存病例及同时段入院的外伤患者。利用SPSS进行数据录入和分析,用logistic回归模型进行单因素和多因素分析筛选出有意义的危险因素。结果经单因素及多因素分析,与乳腺癌发病有关的因素为:月经经期不规则、行经期长、流产史、青霉素过敏史等,月经初潮晚能降低乳腺癌的发病风险。结论月经经期不规则、行经期长、流产史及青霉素过敏史等是乳腺癌危险因素,而月经初潮晚对乳腺癌有保护作用。
Objective To explore the risk factors of breast cancer in women and provide evidence for the prevention and treatment of breast cancer. Methods A case-control study was conducted to investigate the survivals of breast cancer confirmed by histopathology from January 2003 to April 2005 and the traumatic patients admitted to hospital at the same time. Using SPSS for data entry and analysis, using logistic regression model for single factor and multivariate analysis to screen out meaningful risk factors. Results By univariate and multivariate analysis, the factors associated with breast cancer incidence were irregular menstruation, long menstrual cycle, history of abortion, history of penicillin allergy, etc. The incidence of breast cancer was reduced by late menarche. Conclusion Irregular menstruation, long menstrual period, history of abortion and penicillin allergy are risk factors for breast cancer, and late menarche has a protective effect on breast cancer.