无唾液酸基糖蛋白受体(asialoslycoproteinreceptor,ASGPR)是自身免疫性慢性活动性肝炎(CAH)病人表达于肝细胞浆膜外层的一种糖肽。大多数 CAH 病人有 ASGPR 抗体,而且大多数自身免疫性 CAH 病人有对 ASGPR 的T_H 细胞反应。该病患者及其一部分健康亲属中存在的特异性 TS 细咆缺陷,由此产生自身免疫性CAH 仅见于先天决定的 Ts 细咆 ASGPR 特异 Asialoslycoprotein receptor (ASGPR) is a glycopeptide that is expressed on the outer plasma membrane of patients with autoimmune chronic active hepatitis (CAH). Most CAH patients have ASGPR antibodies, and most autoimmune CAH patients have T cell responses to ASGPR. The presence of TS-specific TS defects in this patient population and in some of their health relatives, resulting in autoimmune CAH, is found only in the naive Ts Tsai Ro ASGPR-specific