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目的观察莫西沙星治疗重症老年社区获得性肺炎的临床效果。方法将2014年3月至2015年4月收治的64例重症老年社区获得性肺炎患者分为观察组和对照组,每组32例。对照组使用左氧氟沙星静脉滴注400 mg,1次/d;观察组使用莫西沙星静脉滴注400 mg,1次/d,患者症状明显好转改为口服莫西沙星片400 mg,1次/d。两组疗程均为10 d。观察并比较两组患者的治疗效果。结果观察组临床治疗效果和细菌疗效显著优于对照组,差异有统计学意义(P<0.05)。结论莫西沙星治疗重症老年社区获得性肺炎效果显著,不良反应少,能有效提高恢复速度,应在临床中加以推广和应用。
Objective To observe the clinical effect of moxifloxacin in the treatment of community-acquired pneumonia in severe elderly. Methods Sixty-four patients with severe community-acquired pneumonia admitted from March 2014 to April 2015 were divided into observation group and control group, 32 cases in each group. In the control group, levofloxacin was infused intravenously for 400 mg once daily. In the observation group, moxifloxacin was given intravenously once daily for 400 mg once daily, and the symptoms were improved to be oral moxifloxacin 400 mg once daily . The two courses of treatment were 10 d. Observed and compared the treatment effect of two groups of patients. Results The clinical efficacy and bacterial efficacy of the observation group were significantly better than those of the control group, with statistical significance (P <0.05). Conclusion Moxifloxacin treatment of community-acquired pneumonia in elderly patients with severe effect, fewer adverse reactions, can effectively improve the recovery rate should be promoted in the clinical application.