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为探讨肺癌中红桂木凝集素(ALL)受体的表达及其临床意义,本研究应用凝集素亲和组化法检测45例原发性肺癌(鳞癌25例,腺癌20例),阴性对照采用20例癌旁正常肺组织。凝集素组化显示,28例(62.2%)肺癌和3例(15%)癌旁正常肺组织的红桂木凝集素受体表达阳性,差异具有显著性。红桂木凝集素受体表达与肺癌TNM分期、淋巴结转移、分化程度有关,但与年龄、性别、肿瘤大小、病理类型无关。
In order to investigate the expression and clinical significance of red bayberry lectin (ALL) receptor in lung cancer, 45 cases of primary lung cancer (25 cases of squamous cell carcinoma and 20 cases of adenocarcinoma) were detected by lectin affinity assay, and negative Control using 20 cases of adjacent normal lung tissue. Lectin staining showed that the expression of Lectin red lectin receptor was positive in 28 cases (62.2%) of lung cancer and 3 cases (15%) of adjacent normal lung tissues, the difference was significant. The expression of Lectin receptor was correlated with TNM stage, lymph node metastasis and differentiation of lung cancer, but not with age, gender, tumor size and pathological type.