不同剂量脑预防照射对局限期小细胞肺癌患者的临床观察

来源 :实用临床医药杂志 | 被引量 : 0次 | 上传用户:wwbywbytc
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目的观察局限期小细胞肺癌不同剂量预防性全脑照射(PCI)对降低脑转移和生存率的影响。方法将本院收治的84例局限期小细胞肺癌患者随机分组,根据患者治疗要求分为标准PCI剂量组、较高PCI剂量组和对照组。观察患者两年脑转移发生率、总生存率以及放射性脑损伤引发的不良反应。结果标准剂量PCI组与较高剂量PCI组的2年脑转移发生率经比较,差异无统计学差异。发生脑转移患者与未发生脑转移患者的中位生存时间分别为17.6个月和47.4个月;标准剂量组的1年和3年生存率高于较高剂量组,但差异不明显。结论局限期小细胞肺癌术后
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