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目的研究新疆哈萨克族高尿酸血症与肥胖及相关体脂指标的关系。方法随机抽取新疆阿勒泰地区医院哈萨克族门诊体检及住院的病人339例为研究对象,其中高尿酸组172例,尿酸正常组167例。测量身高、体重、腰围、臀围,并计算体脂相关指标。结果体脂肪相关指标中体重、腰围、臀围、体质指数(BMl)、腰围/身高(WHTR)均为高尿酸组高于对照组,差异有统计学意义(P<0.05);相关性分析中,血尿酸与体重、腰围、臀围、BMI、腰臀比(WHR)、WHTR呈显著正相关;4个指标的受试者工作特征曲线(ROC)曲线分析:曲线下面积以BMI和腰围最大,BMI为0.625(95%CI:0.553～0.697),腰围为0.606(95%CI:0.534～0.678),BMI最佳切点为27,腰围的最佳切点值为103;多元逐步回归分析显示,BMI、WHR是影响血尿酸的主要相关危险因素。结论体脂含量及分布与哈萨克族高尿酸血症存在着密切的关系,而BMI、WHR是影响高尿酸血症的危险因素。因此,控制体重并保持健康的体型对于防治哈萨克族高尿酸血症具有重要意义。
Objective To study the relationship between hyperuricemia and obesity and related body fat index in Xinjiang Kazak. Methods A total of 339 Kazak outpatient clinics and inpatients were randomly selected from Altay district hospitals in Xinjiang, including 172 patients with hyperuricemia and 167 patients with normal uric acid. Measure height, weight, waist circumference, hip circumference, and calculate body fat-related indicators. Results Body fat, waist circumference, hip circumference, body mass index (BMl) and waist circumference / height (WHTR) were significantly higher in the hyperuric group than in the control group (P <0.05). Correlation analysis , Serum uric acid and body weight, waist circumference, hip circumference, BMI, WHR, WHTR was significantly positive correlation; four indicators of the working characteristics curve (ROC) curve analysis: the area under the curve to BMI and waist circumference , The BMI was 0.625 (95% CI: 0.553-0.697), the waist circumference was 0.606 (95% CI: 0.534-0.678), the best cut point of BMI was 27 and the best cut point value of waist circumference was 103. Multivariate stepwise regression analysis , BMI, WHR are the main related risk factors affecting serum uric acid. Conclusion Body fat content and distribution are closely related to Kazakh hyperuricemia, while BMI and WHR are the risk factors of hyperuricemia. Therefore, the control of body weight and maintain a healthy body shape for the prevention and treatment of Kazakh hyperuricemia has important significance.