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神经元是一种可兴奋性细胞,能迅速以一种可控制方式传递电化学信号。神经元内对化学和电信号刺激做出反应的主要信使是Ca2+。Ca2+通过质膜上的电压依赖性和配体型钙通道进入胞质内,是突触前膜释放神经递质的关键信号。胞内Ca2+调节系统的失调将造成突触功能失调、
Neurons are excitable cells that rapidly transmit electrochemical signals in a controlled manner. The main messenger in neurons that responds to chemical and electrical stimuli is Ca2 +. Ca2 + enters the cytoplasm through the voltage-dependent and ligand-type calcium channels on the plasma membrane and is the key signal for the presynaptic membrane to release neurotransmitters. Disorders of the intracellular Ca2 + regulatory system will result in synaptic dysfunction,