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目的:浅谈医院抗菌药物不合理应用现状。方法:随机抽取该院2012年1~6月门诊及住院患者处方90000张,对该院应用抗菌药物情况进行系统分析,探讨抗菌药物使用情况。结果:90000张处方中抗菌药物处方52200张,占总处方数的58%,其中,不合理应用抗菌药物处方10962张,占抗菌药物处方的21%。主要表现在给药次数不合理,溶媒选择不当,联合用药不当,应用抗菌药物指征不明确或无指征,抗菌药物应用起点高。结论:药学人员应结合临床需要,认真审核处方,及时与临床医师沟通,发挥药师的干预作用;临床医生也应不断加强药学知识的学习,准确掌握各种抗菌药物的适应证,结合患者病情合理用药;使临床用药更趋安全、有效、经济,更好地为患者服务。
Objective: To discuss the irrational application of antimicrobial drugs in hospitals. Methods: A total of 90 000 prescriptions for outpatients and inpatients from January to June in 2012 in our hospital were randomly selected to conduct a systematic analysis on the use of antimicrobial agents in the hospital to explore the use of antimicrobial agents. Results: Of the 90 000 prescriptions, 52 200 prescriptions of antibacterials were prescribed, accounting for 58% of the total number of prescriptions. Of these, 10 962 antibacterial prescriptions were used unreasonably, accounting for 21% of the prescriptions of antibacterials. Mainly in the number of unreasonable administration, improper solvent selection, improper combination, the application of antimicrobial indications is not clear or no indication, antimicrobial application of high starting point. Conclusion: The pharmacy staff should conscientiously review the prescription, timely communicate with the clinician, and play the role of pharmacist intervention. The clinician should also continuously strengthen the study of pharmacy knowledge, accurately grasp the indications of various antimicrobial agents, combined with the patient’s condition is reasonable Medication; make clinical medication more safe, effective, economical and better service to patients.