鸟嘌呤核苷酸调节蛋白(GTP,G蛋白)是一类异源三聚体,它是细胞表面受体与细胞内的酶系统(如肾上腺素能受体复合物)之间的传导信号。编码G蛋白基因表达的改变,或是由于微生物毒素使其发生翻译后修饰,都会出现信号异常。鉴于G蛋白对肺功能的重要意义,本文作者研究了未感染及感染卡氏肺孢子虫(P.c.)的免疫抑制白鼬 Guanine nucleotide regulatory proteins (GTPs, G proteins) are a class of heterotrimers that are signaling signals between cell surface receptors and intracellular enzyme systems such as adrenergic receptor complexes. Altered gene expression of G protein changes, or because of microbial toxins post-translational modification occurs, there will be abnormal signal. In view of the importance of G protein for lung function, the authors investigated the immunosuppressive ferret uninfected and infected with Pneumocystis carinii (P.c.)