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目的:观察魔芋葡甘露聚糖(KGM)对肥胖伴高血压病患者的体重指数、血压、血脂、血糖等的影响。方法:68例肥胖伴高血压病患者在不改变原有治疗的基础上给予KGM口服,治疗12周后评价其对体重指数、血压、血脂、血糖等的影响。结果:KGM降低体重指数、血压、总胆固醇、甘油三酯、低密度脂蛋白、糖基化血红蛋白(P<0.01);升高高密度脂蛋白(P<0.01)。结论:KGM防治肥胖伴高血压病及肥胖相关疾病前景广阔。
Objective: To observe the effect of konjac glucomannan (KGM) on body mass index, blood pressure, blood lipid, blood glucose and other factors in obese patients with hypertension. Methods: Sixty-eight patients with obesity and hypertension were given oral KGM without changing the original treatment. After 12 weeks of treatment, their effects on body mass index, blood pressure, blood lipid and blood sugar were evaluated. Results: KGM decreased body mass index, blood pressure, total cholesterol, triglyceride, low density lipoprotein and glycosylated hemoglobin (P <0.01) and elevated high density lipoprotein (P <0.01). Conclusion: KGM has a bright future in the prevention and treatment of obesity with hypertension and obesity-related diseases.