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目的 了解社区获得性快生长型非结核分支杆菌肺病的临床特点。方法 对 1986年 1月～ 1997年间痰抗酸杆菌培养阳性 390 7例中 ,经菌型鉴定证明为快生长型非结核分支杆菌肺病者 5 8例进行回顾性分析。结果 按 Runyon分类法 ,感染 型偶然分支杆菌 38例 ,龟分支杆菌 2 0例 ;男 39例 ,女 19例 ;病程 8～ 40年 ;主要症状咳嗽、咯白粘痰、咯血、发热 ;X线胸片两侧受累者 6 0 .3% ,左侧 2 4.1% ,右侧 15 .5 % ;对异烟肼、链霉素、乙胺丁醇、利福平、对氨基水杨酸、丙硫异烟胺耐药率很高 ,而对卡那霉素耐药率相对较低。结论 快生长型非结核分支杆菌肺病者病程长、症状不特异、耐药率高、抗结核治疗疗效差。
Objective To understand the clinical characteristics of community-acquired fast-growing non-tuberculous mycobacterium tuberculosis. Methods A total of 390 7 positive sputum acid-fast bacilli cultures were collected from January 1986 to January 1997. Fifty-eight cases of fast-growing non-tuberculous mycobacterium tuberculosis confirmed by bacterial identification were retrospectively analyzed. Results According to the Runyon classification, 38 cases of Mycobacterium vaccae and 20 cases of Mycobacterium turtle were found. There were 39 males and 19 females with a course of 8 to 40 years. The main symptoms were cough, phlegm, hemoptysis and fever. X-ray Chest radiographs were 60.3% on both sides of the chest, 21.1% on the left and 15.5% on the right. The isoniazid, streptomycin, ethambutol, rifampin, p-aminosalicylic acid, Sulfanilamide resistance rate is high, while kanamycin resistance rate is relatively low. Conclusion The fast-growing non-tuberculosis mycobacterium tuberculosis patients have a long course of disease, the symptoms are not specific, the drug resistance rate is high, and the curative effect of anti-tuberculosis therapy is poor.