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大动脉炎是一种罕见的慢性非特异性血管炎,主要侵犯主动脉及其主要分支,其中约10%～30%的病例可累及冠状动脉(冠脉)造成严重临床后果。大动脉炎累及冠脉时多表现为冠脉开口或近端的狭窄和闭塞。无创影像诊断技术的进展使该病的早期诊断和监测水平得到提高。计算机断层扫描(CT)与核磁共振(MRI)可以发现狭窄前的管壁炎症损伤。尽管糖皮质激素和免疫抑制剂可以改善大动脉炎的症状,但药物减量后仍然容易复发。血管成形术早期通畅率较满意,但中远期再狭窄率仍然很高。药物涂层支架可能成为解决再狭窄问题的一个新途径。
Polyarteritis is a rare chronic nonspecific vasculitis that mainly affects the aorta and its major branches. Approximately 10% to 30% of the cases can involve the coronary arteries (coronary arteries) causing serious clinical consequences. Arteriositis involving the coronary arteries more than the performance of the opening or proximal coronary stenosis and occlusion. Advances in noninvasive imaging diagnostic techniques have led to an increase in the early diagnosis and monitoring of the disease. Computed tomography (CT) and magnetic resonance imaging (MRI) can detect pre-stenosis of the wall inflammation. Although glucocorticoids and immunosuppressive agents can ameliorate the symptoms of aortic arteritis, the drug is still prone to relapse after dose reduction. The early patency of angioplasty was satisfactory, but the rate of restenosis in the long-term was still high. Drug-coated stents may be a new way to solve the problem of restenosis.