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郎格罕细胞组织细胞增生症(LCH)是一种非肿瘤性LC异常增生,或反应性增殖性疾病,此种增生可能是内源性或外源性刺激导致免疫调节功能紊乱所致[1]。《实用儿科学》将此病分为六型:Ⅰ型或称内脏病变及皮肤侵犯型(L-S),Ⅱ型或称骨损害伴中度内脏侵犯型(中间型),Ⅲ型或称骨损害伴轻
Langerhans cell histiocytosis (LCH) is a non-neoplastic LC abnormal proliferation, or reactive proliferative disease that may be caused by endogenous or exogenous stimulation leading to dysregulation of immune regulation [1 ]. “Practical Pediatrics” will be divided into six types of disease: Ⅰ or visceral lesions and skin-invasive type (LS), type Ⅱ or bone damage with moderate visceral infringement (intermediate), Ⅲ or bone damage With light