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目的评价中西药结合治疗病毒性心肌炎的临床疗效。方法检索中国生物医学文献数据库(CBM)、中国期刊全文数据库、中文科技期刊数据库(维普)、万方资源文献数据库,对符合纳入标准的随机对照试验进行Meta分析。结果共纳入7篇临床研究与西药组比较,中西药结合组可显著提高临床治疗效果[95%CI(2.60,6.58),P<0.01]。结论中西药结合可显著提高病毒性心肌炎患者的临床疗效,但由于国内中药研究整体质量有待提高,尚需进行进一步高质量随机对照试验加以证实。
Objective To evaluate the clinical efficacy of traditional Chinese and western medicine in the treatment of viral myocarditis. Methods Meta-analysis was performed on randomized controlled trials that met the inclusion criteria in China Biomedical Literature Database (CBM), Chinese Journal Full-text Database, Chinese Science and Technology Periodical Database (VIP) and Wanfang Resources Literature Database. Results A total of 7 clinical studies were included in the study. Compared with the western medicine group, the combination of Chinese and western medicine can significantly improve the clinical effect [95% CI (2.60,6.58), P <0.01]. Conclusion The combination of Chinese and Western medicine can significantly improve the clinical efficacy of patients with viral myocarditis, but due to the overall quality of domestic traditional Chinese medicine to be improved, further high-quality randomized controlled trials need to be confirmed.