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12只家兔暴露于模拟海拔5000m高度,每天4h,七天后,家兔再暴露于相同海拔高度,停留2.5h,并测量脑脊液和动脉血的pH以及肺通气量。结果表明,脑脊液pH、动脉血pH和肺通气量分别由海平时的7.321、7.435和1.43L/min增加到7.386、7.514和2.58L/min。这说明,家兔经间断减压缺氧适应后再处于急性缺氧时所发生的持续性过度通气,与脑脊液pH是否能得到调解和代偿可能无关。
Twelve rabbits were exposed to a simulated height of 5000 m. After 4 h and 7 days, the rabbits were exposed to the same altitude for 2.5 h. The pH of the cerebrospinal fluid and arterial blood and the pulmonary ventilation were measured. The results showed that CSF pH, arterial pH and pulmonary ventilation increased from 7.321, 7.435 and 1.43L / min at sea level to 7.386, 7.514 and 2.58L / min, respectively. This shows that the rabbit after intermittent decompression and hypoxia adaptation in acute hypoxia occurs when the sustained hyperventilation, and cerebrospinal fluid pH can be mediation and compensation may be irrelevant.