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目的了解门诊围绝经期综合征患者的特征与需求,以期为其治疗和护理提供参考。方法对就诊于江苏省中医院门诊的围绝经期综合征患者进行一般情况、改良Kupperman Index评分(KI)、绝经期生存质量(MENQOL)调查及血清E_2、FSH和LH测量。结果患者平均年龄(50.51±3.82)岁,平均绝经年龄(49.10±4.87)岁,38.5%的患者出现月经紊乱,61.5%的患者已绝经。病情以轻中度为主,发生率居前5位的症状依次为血管舒缩症状(98.5%)、疲劳(91.5%)、感觉异常(82.5%)、失眠(81%)和神经过敏、焦虑(74%)。患者生存质量较差,不同病情的患者MENQOL中4个维度得分除性生活维度外差异均有统计学意义(P<0.01)。随着病情的加重,患者的E2呈下降趋势,FSH和LH呈上升趋势。结论门诊围绝经期综合征患者病情以轻中度为主,躯体和心理症状对其生存质量影响较大,患者病情的严重程度可能与血清激素水平具有一定的相关性。
Objective To understand the characteristics and needs of outpatients with menopausal syndrome in order to provide reference for their treatment and nursing. Methods The general situation, improved Kupperman Index (KI), menopausal quality of life (MENQOL), serum E2, FSH and LH were measured in patients with perimenopausal syndrome attending Jiangsu Provincial Hospital of Traditional Chinese Medicine. Results The average age of patients (50.51 ± 3.82) years, the average age of menopause (49.10 ± 4.87) years, 38.5% of patients with menstrual disorders, 61.5% of patients have been menopause. The symptoms were mild to moderate with the top five symptoms being vasomotor symptoms (98.5%), fatigue (91.5%), sensory abnormalities (82.5%), insomnia (81%) and neuroticism and anxiety (74%). Patients with poor quality of life, different conditions in patients with MENQOL scores in four dimensions except sex life were significantly different (P <0.01). With the exacerbation of disease, the decline of E2 in patients and the rising of FSH and LH. Conclusion The prevalence of outpatient perimenopausal syndrome is mild to moderate, somatic and psychological symptoms have a significant impact on the quality of life. The severity of the disease may be related to serum hormone levels.