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文章就连续性血液净化技术在心力衰竭(HF)中的临床应用作综述。HF是各种心脏疾病的严重阶段或终末阶段,病情发展至晚期,发生肾功能不全,进一步加重水、钠潴留,形成难治性水肿,如此形成恶性循环,并逐步发展为顽固性心力衰竭(RHF)。但对于合并肾功能损害及HF晚期或老年合并多脏器功能障碍甚至衰竭的患者,连续性血液净化治疗时血流动力学稳定,可以清除体内多余的容量负荷和小分子毒素,同时具有清除炎症介质的作用,对于常规药物无效的RHF,不仅能改善患者的容量状况,而且改善失代偿患者的临床表现,从而使HF得到缓解。
The article summarizes the clinical application of continuous blood purification in heart failure (HF). HF is a serious stage or terminal stage of various heart diseases, the progression of the disease to advanced stage, renal insufficiency, and further increase water and sodium retention, the formation of refractory edema, so the formation of a vicious circle and the progressive development of refractory heart failure (RHF). However, for patients with renal dysfunction and HF complicated with multiple organ dysfunction or even failure, the hemodynamic stability of continuous blood purification treatment can remove the excess capacity load and small molecule toxins in the body, as well as have the effect of clearing inflammation The role of media, RHF, which is ineffective with conventional drugs, not only improves the patient’s capacity status but also improves the clinical manifestations of the decompensated patients, thereby allowing HF to be alleviated.