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目的 :分析生殖器流行性卡波西氏肉瘤 (Kaposi sSarcoma简称KS)的发病情况、临床特征及治疗方法。资料和方法 :1986年 6月至 1996年 12月 ,巴黎第十二大学医学院HenriMondor医院肿瘤放疗科共收治 64 5例爱滋病KS病人 ,其中 71例有阴茎及阴囊病变。单发于阴茎或阴囊有 12例 ,其余 5 9例均合并有其它部位的皮肤侵犯。中位年龄 3 7岁 ,9例有排尿困难 ,13例有水肿或 /和疼痛。均采用放射治疗 ,选用低能 ( 4 5KV)X线 ,大野照射10Gy/4次·周 ,根据病变反应 ,休息 15天 ,缩野再予 5～ 10Gy。结果 :所有病人均获客观上的缓解和器官功能的恢复。在 71例共 189个病变部位中 ,完全反应率 2 8% ,部分反应率 66% ,6%无反应。所有病人均获随访 ,平均随访期 7 5个月。结论 :发生于生殖器的流行性KS少见。放疗对本病可取得满意结果 ;尿道狭窄为放疗的主要并发症
Objective: To analyze the incidence, clinical features and treatment of genital epidemic Kaposi sSarcoma (KS). Materials and Methods: From June 1986 to December 1996, the Cancer Radiotherapy Department of the Henri Mondor Hospital, Faculty of Medicine, Twelfth University in Paris received a total of 64 5 AIDS KS patients, of which 71 cases had penile and scrotal lesions. There were 12 cases in the penis or scrotum, and the remaining 519 cases were accompanied by other skin invasion. The median age was 37 years. Nine patients had difficulty urinating and 13 patients had edema or/and pain. All patients were treated with radiation therapy, using low-energy (4 5KV) X-rays. Ono Irradiated with 10 Gy/4 times a week. According to the lesion reaction, rest for 15 days and shrinking for 5 to 10 Gy. RESULTS: All patients were objectively relieved and their organ function restored. In a total of 189 lesions in 71 cases, the complete response rate was 28%, the partial response rate was 66%, and 6% had no response. All patients were followed up for an average of 75 months. Conclusion: The epidemic KS occurring in the genitalia is rare. Radiotherapy can achieve satisfactory results for this disease; urethral stricture is the main complication of radiotherapy