自ALLHAT试验和美国高血压预防、检测、评价和治疗的全国联合委员会第七次报告(JNCVII)公布以来,临床上普遍重视噻嗪类利尿剂的使用。本研究采用随机对照方法,旨在探讨氢氯噻嗪用于治疗原发性高血压的适宜剂量。1材料和方法1.1入选标准按1999年WHO/ISH标准,连续3次非同日坐位收 Since the release of the ALLHAT trial and the Seventh National Committee report on Prevention, Detection, Evaluation and Treatment of Hypertension (JNCVII) in the United States, there has been a general clinical emphasis on the use of thiazide diuretics. This study used a randomized controlled trial to explore the appropriate dose of hydrochlorothiazide for the treatment of essential hypertension. 1 Materials and methods 1.1 Selection criteria According to 1999 WHO / ISH standards, three consecutive non-sitting seats received