肠应激综合征 (IBS)是最常见的胃肠功能紊乱性疾病之一 ,以慢性复发性腹痛和肠功能紊乱为主要症状。有报道认为 5- HT3受体拮抗剂对 IBS可能有治疗价值 ,为评价阿洛司琼 (alosetron)治疗 IBS的效果和安全性 ,作者进行了随机、双盲和安慰剂对照研究。选择美国 1 1 9个中心 1 463 Intestine stress syndrome (IBS) is one of the most common gastrointestinal disorders, chronic recurrent abdominal pain and intestinal disorders as the main symptoms. It has been reported that 5-HT3 receptor antagonists may have therapeutic value for IBS. To evaluate the efficacy and safety of alosetron in the treatment of IBS, the authors conducted randomized, double-blind and placebo-controlled studies. Select the United States 1 1 9 centers 1 463