Ultra-reliable and low-latency communications(URLLC) has become a fundamental focus of future industrial wireless sensor net-works(IWSNs). With the evolution of automation and process control in industrial environments, the need for increased reliabilityand reduced latencies in wireless communications is even pronounced. Furthermore, the 5G systems specifically target the URLLCin selected areas and industrial automation might turn into a suitable venue for future IWSNs, running 5G as a high speed inter-process linking technology. In this paper, a hybrid multi-channel scheme for performance and throughput enhancement of IWSNsis proposed. The scheme utilizes the multiple frequency channels to increase the overall throughput of the system along with theincrease in reliability. A special purpose frequency channel is defined, which facilitates the failed communications by retransmis-sions where the retransmission slots are allocated according to the priority level of failed communications of different nodes. Ascheduler is used to formulate priority based scheduling for retransmission in TDMA based communication slots of this channel.Furthermore, in carrier-sense multiple access with collision avoidance(CSMA/CA) based slots, a frequency polling is introducedto limit the collisions. Mathematical modelling for performance metrics is also presented. The performance of the proposed schemeis compared with that of IEEE802.15.4e, where the performance is evaluated on the basis of throughput, reliability and the num-ber of nodes accommodated in a cluster. The proposed scheme offers a notable increase in the reliability and throughput over theexisting IEEE802.15.4e Low Latency Deterministic Networks(LLDN) standard. Ultra-reliable and low-latency communications (URLLC) has become a fundamental focus of future industrial wireless sensor net-works (IWSNs). With the evolution of automation and process control in industrial environments, the need for increased reliability and reduced latencies in wireless communications even this 5G systems specifically target the URLLCin selected areas and industrial automation might turn into a suitable venue for future IWSNs, running 5G as a high speed inter-process linking technology. In this paper, a hybrid multi-channel scheme for performance and throughput enhancement of IWSNsis proposed. The scheme utilizes the multiple frequency channels to increase the overall throughput of the system along with the increase in reliability. A special purpose frequency channel is defined, which facilitates the failed communications by retransmis-sions where the retransmission slots are allocated according to the priority level of failed communications o f different nodes. Ascheduler is used to formulate priority based scheduling for retransmission in TDMA based communication slots of this channel. Morerther, in carrier-sense multiple access with collision avoidance (CSMA / CA) based slots, a frequency polling is introducedto limit the collisions The performance of the proposed scheme is compared with that of IEEE 802.15.4e, where the performance is evaluated on the basis of throughput, reliability and the num-ber of nodes accommodated in a cluster. proposed scheme offers a not can increase in the reliability and throughput over theexisting IEEE 802.15.4e Low Latency Deterministic Networks (LLDN) standard.