论文部分内容阅读
采用ＲＩＡ法检测７１例胃病患者血清垂体泌乳素（ＰＲＬ）水平。结果：３８例慢性肾衰患者血清ＰＲＬ显著高于正常对照组（Ｐ＜０．００１）；３３例慢性肾炎患者ＰＲＬ也显著高于正常对照组，（Ｐ＜０．００１）；而慢性肾衰患者较慢性肾炎患者显著升高（Ｐ＜０．００１）；各组男女之间比较无显著性差异（Ｐ均＞０．０５）。肾病患者血清ＰＲＬ值与血清钙离子浓度呈负相关（ｒ＝－０．６０１０，Ｐ＜０．０１）；与血清肌酐和尿素氮呈正相关（ｒ＝０．５２０８，Ｐ＜０．０１；ｒ＝０．５９０７，Ｐ＜０．０１）。本实验结果表明：血清ＰＲＬ随肾病的严重程度而升高，提示对肾病患者测定血清ＰＲＬ可以作为肾脏功能损害程度的一项有关指标。
Serum pituitary prolactin (PRL) levels were measured by RIA in 71 patients with gastric disorders. Results: The PRL of 38 patients with chronic renal failure was significantly higher than that of the normal control group (P <0.001). The PRL of 33 patients with chronic nephritis was significantly higher than that of the normal control group (P <0.001) Patients with chronic nephritis were significantly higher (P <0.001); There was no significant difference between men and women in each group (all P> 0.05). Serum PRL in patients with nephropathy was negatively correlated with serum calcium concentration (r = -0.6010, P <0.01), and positively correlated with serum creatinine and urea nitrogen (r = 0.5208, P <0.01; r = 0.5907, P <0.01). The experimental results show that: the serum PRL increased with the severity of nephropathy, suggesting that serum PRL in patients with nephropathy can be used as an indicator of renal impairment.