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目的:评价降阶梯疗法联合支气管肺泡灌洗治疗急性脑卒中合并肺部感染的疗效。方法:将80例急性脑卒中合并肺部感染患者随机分成两组。治疗组40例,采用抗菌药物降阶梯疗法联合支气管肺泡灌洗治疗策略;对照组40例,采用常规抗菌药物治疗。分别观察其临床疗效、细菌转阴率、肺部感染吸收天数、入住NICU天数。结果:治疗组的有效率及细菌转阴率明显高于对照组(P<0.05),而平均肺部感染吸收时间和平均ICU住院时间明显少于对照组(P<0.01)。结论:以降阶梯疗法联合支气管肺泡灌洗为基础的局部与全身抗生素联合治疗策略,是治疗急性脑卒中患者合并肺部感染的有效方法。
OBJECTIVE: To evaluate the efficacy of combined descending ladder therapy with bronchoalveolar lavage in the treatment of acute stroke complicated with pulmonary infection. Methods: Eighty patients with acute stroke complicated with pulmonary infection were randomly divided into two groups. The treatment group of 40 cases, the use of anti-bacterial anti-step ladder therapy combined with bronchoalveolar lavage treatment strategy; control group of 40 cases, the use of conventional antimicrobial drugs. The clinical efficacy, the rate of bacterial negative conversion, the days of lung infection absorption, the number of days of NICU stay were observed. Results: The effective rate of the treatment group and the rate of negative bacteria were significantly higher than those of the control group (P <0.05). However, the average lung infection absorption time and the average ICU stay time in the treatment group were significantly less than those in the control group (P <0.01). Conclusion: The combined local and systemic antibiotic treatment strategy based on the combination of descending ladder therapy and bronchoalveolar lavage is an effective method for the treatment of acute pulmonary stroke complicated with pulmonary infection.