前列腺素(PG)是广泛存在于人体各器官的组织激素。近年来对前列腺素的生理、药理作用以及病理状况下的变化进行了广泛的研究,发现在创伤、感染、休克等情况下前列腺素(PGE、PGF)合成增加,参与休克的发病,某些前列腺素以及影响前列腺素合成酶系的药物在休克中可发挥治疗作用,本文就此作一综述。 Prostaglandins (PGs) are tissue hormones widely found in various organs of the human body. In recent years, prostaglandin physiology, pharmacological effects and changes under pathological conditions were extensively studied and found that in trauma, infection, shock and so on prostaglandin (PGE, PGF) synthesis increased, involved in the pathogenesis of shock, some of the prostate Superoxide dismutase and prostaglandin synthetase-like drugs play a therapeutic role in shock. This article reviews the findings.