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研究长期小剂量低剂量率电离辐射照射对老年痴呆病的影响，为研究小剂量电离辐射对中枢神经系统影响及老年痴呆的病因学提供对人类的直接观察资料。方法在中国广东省阳江高本底地区进行老年痴呆病患病率的现况调查，筛选阶段应用长谷川智力量表，确诊阶段应用老人健康状况调查专门用表。以美国精神疾病诊断和统计手册修订第３版（ＤＳＭⅢ－Ｒ）为诊断标准。结果共调查６５岁及以上老年人１０１８人，其中高本底地区５１３人，对照地区５０５人，按ＤＳＭⅢ－Ｒ为诊断标准，共确诊老年痴呆病６１例，其中高本底地区３１例，对照地区３０例。总患病率为５．９９％，高本底地区为６．０４％，对照地区为５．９４％。结论该高本底地区和对照地区老年痴呆患病率差异无显著性
To study the effects of long-term low-dose and low-dose ionizing radiation on Alzheimer’s disease and to provide a direct observation of human beings in order to study the effect of low dose ionizing radiation on central nervous system and the etiology of Alzheimer’s disease. Methods The prevalence of Alzheimer’s disease was surveyed in the high background area of Yangjiang, Guangdong Province, China. The Hasegawa Intelligence Scale was used in the screening stage, and the special table of the elderly health status survey was used in the diagnosis stage. Diagnostic and Statistical Manual of American Psychiatry, Revision 3 (DSM III-R) as diagnostic criteria. Results A total of 1018 elderly people aged 65 and above were surveyed, including 513 in the high background area and 505 in the control area. According to DSMⅢ-R, 61 cases were diagnosed as Alzheimer’s disease, of which 31 cases were high background area. Area 30 cases. The overall prevalence rate was 5.99%, high background area 6.04%, control area 5.94%. Conclusion There is no significant difference in the prevalence of dementia between the high background area and the control area