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目的探讨血管肉瘤的临床病理特征、治疗方式及预后。方法对2010年1月至2015年10月于四川大学华西医院就诊且经病理科确诊的29例血管肉瘤患者的临床病理资料进行回顾性分析。结果本组29例患者,占同期所收治软组织肿瘤病例总数的0.60%(29/4 574)。中位年龄为53岁。出现复发或转移的中位时间为6.8月。局部复发14例,占48.3%,远处转移11例,占37.9%,转移部位依次为淋巴结5例,肺5例,肝脏2例,骨1例,其他3例。生存期从治疗开始之日计算,全组生存期为4~64月,平均19.7月。随访时间为4~74月(平均34月),目前健在11例,死亡16例。2例患者失访,随访率93.1%。结论血管肉瘤临床上少见,其侵袭性强,预后差。
Objective To investigate the clinicopathological characteristics, treatment and prognosis of angiosarcoma. Methods The clinical and pathological data of 29 patients with angiosarcoma treated by West China Hospital of Sichuan University from January 2010 to October 2015 were retrospectively analyzed. Results The group of 29 patients, accounting for 0.60% (29/4 574) of the total number of soft tissue tumors treated during the same period. The median age is 53 years. The median time to relapse or metastasis was 6.8 months. Local recurrence in 14 cases, accounting for 48.3%, remote metastasis in 11 cases, accounting for 37.9%, followed by lymph node metastasis in 5 cases, 5 cases of lung, liver in 2 cases, bone in 1 case, the other 3 cases. Survival calculated from the start of treatment, the whole group survival was 4 to 64 months, an average of 19.7 months. The follow-up period was from April to July (average 34 months). Currently, 11 cases were alive and 16 died. Two patients were lost to follow-up, with a follow-up rate of 93.1%. Conclusion Angiosarcomas are rare in clinic, they have strong invasion and poor prognosis.