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激素治疗子宫内膜异位症已被广泛应用,以雌激素/孕酮合剂应用最多。但激素的选择或剂量尚未一致,有副作用且有潜在危险性。因为在大多数研究中,疾病诊断以后只能靠临床估计进行随访,故此法之优点不易评价。亦有报导用孕激素治疗者,治疗后有闭经期延长或规律的撤退性出血,因未能显示具有令人信服的优点而未广泛应用。强雄激素性药物的治疗收效迅速,但男性化改变不受妇女欢迎,而且不能长期持续应用,达到治愈疾病的效果。合成激素Danazol是一种合成代谢性、弱雄激素性、非孕激素性、非雌激素性药物。它抑制卵巢类固醇激素的分泌,致使体内雌激素及孕激素水平降低,从而排卵停止。也可直接作用于子宫内膜,使之萎缩。本文研究两组患者共50例,27例用Danazol治
Hormonal treatment of endometriosis has been widely used to estrogen / progesterone mixture most widely used. However, the choice of hormone or dose has not yet been consistent, there are side effects and potentially dangerous. Because in most studies, after the diagnosis of the disease can only rely on clinical estimates follow-up, so the advantages of this method is not easy to evaluate. There have also been reports of progestin-treated patients who had prolonged amenorrhea or regular withdrawal bleeding after treatment and were not widely used because of their lack of convincing advantages. Strong androgen treatment of drugs with rapid success, but masculine changes are not welcome by women, and can not be sustained long-term application to achieve the effect of curing the disease. Synthetic hormone Danazol is an anabolic, weak androgenic, non-progestogenic, non-estrogenic drug. It inhibits the secretion of ovarian steroid hormones, resulting in reduced levels of estrogen and progesterone in the body, which ovulation stopped. Can also act directly on the endometrium, making it shrink. This study studied a total of 50 patients in both groups, 27 patients treated with Danazol