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目的探讨2型糖尿病与非酒精性脂肪性肝病(NAFLD)的相关性。方法对656例确诊2型糖尿病患者行血糖、血脂、肝功能等生化指标检测和肝脏B超检查。结果①656例糖尿病患者B超证实脂肪肝430例,占65.54%;②分脂肪肝组(430例),无脂肪肝组(226例):脂肪肝组空腹血糖(FBG)、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、丙氨酸氨基转移酶(ALT)、谷氨酰转肽酶(GGT)、收缩压(SBP)、舒张压(DBP),体重指数(BMI)、腰围/臀围比值(WHR)等均值明显升高(P<0.05或P<0.01),HDL-C均值明显降低(P<0.05)。结论糖尿病合并脂肪肝患者存在明显脂代谢紊乱和中央型肥胖,血脂紊乱、肥胖、高血压是其独立危险因素。
Objective To investigate the relationship between type 2 diabetes and nonalcoholic fatty liver disease (NAFLD). Methods 656 patients with type 2 diabetes diagnosed with blood glucose, blood lipids, liver function and other biochemical markers and liver B ultrasound examination. Results ① There were 430 fatty liver cases (65.54%) confirmed by B ultrasound in 656 cases of diabetic patients. ② The levels of fasting blood glucose (FBG) and total cholesterol (TC) in steatosis group (430 cases) and no steatosis group (226 cases) (TG), LDL-C, ALT, GGT, SBP, DBP, , Body mass index (BMI) and waist circumference / hip ratio (WHR) were significantly increased (P <0.05 or P <0.01), mean HDL-C was significantly lower (P <0.05). Conclusion Patients with diabetes mellitus and fatty liver have obvious lipid metabolism disorder and central obesity, dyslipidemia, obesity and hypertension are independent risk factors.