Ｆａｓ（ＣＤ９５／ＡＰＯ－１）属于肿瘤坏死因子超家族的一员，它广泛表达于多种哺乳动物的细胞。当Ｆａｓ与Ｆａｓ配体或技Ｆａｓ抗体结合，即可激发靶细胞的凋亡过程。大量研究表明，肿瘤细胞表面ＦａｓＬｉｇａｎｄ表达增加；许多证据显示肿瘤患者与正常人的外周血淋巴细 Fas (CD95/APO-1) is a member of the tumor necrosis factor superfamily and it is widely expressed in a variety of mammalian cells. When Fas binds with a Fas ligand or a technical Fas antibody, the apoptosis of the target cells can be stimulated. A large number of studies have shown that the expression of FasLigand on the surface of tumor cells increases; many evidences show that the peripheral blood lymphocytes of tumor patients and normal people are fine