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目的 :了解海洛因依赖者丙型肝炎病毒感染情况及其相关危险因素的关系。方法 :将 1 98例海洛因依赖患者的丙型肝炎病毒检测的结果与一般资料、临床特点、乙肝三系结果及肝功能检查结果通过 L ogistic回归模型进行回顾性分析、比较。结果 :海洛因依赖患者抗 -HCV阳性率高于国内自然人群低于国外静脉海洛因依赖者。海洛因依赖患者抗 -HCV阳性的可能性与丙氨酸转氨酶 ( AL T)、海洛因的使用方式有显著的正相关性 ,乙肝病毒的感染指标与本资料所列的可能危险因素无显著的相关关系。结论 :静脉注射的海洛因依赖者可能是 HCV的高危人群 ,HCV可能较 HBV更易传染和引起肝功能变化及慢性化 ,丙型肝炎( HCV)应是对海洛因依赖患者肝炎预防和医务人员保健的重点。
Objective: To understand the relationship between hepatitis C virus infection and related risk factors in heroin addicts. METHODS: The results of HCV detection in 1988 heroin addicts were compared with general data, clinical features, results of the three series of hepatitis B, and liver function tests by using L ogistic regression models. Results: The positive rate of anti-HCV in heroin addicts was higher than that in domestic natural populations. The likelihood of anti-HCV positive in heroin-dependent patients is significantly positively correlated with the use of alanine aminotransferase (AL T) and heroin. There is no significant correlation between the infection index of hepatitis B virus and the possible risk factors listed in this data. . Conclusion: Intravenous heroin addicts may be a high-risk group of HCV, HCV may be more easily infected than HBV and cause liver function changes and chronicity, hepatitis C (HCV) should be the focus of hepatitis prevention and medical personnel care of heroin dependence patients. .